I love this quote, stretching out my interpretation to daily life, is the acknowledgement that things can and go wrong ( Murphy's law ) and we should not stress too much about what could happen, or freak out when it happens but rather do our best to be prepared.
We should prepare for failure and lay out steps and procedures to mitigate and recover quickly and effectively.
(And this best that we can do, really depends from the resources we have available, the level of risk we want to take and the amount of loss we are able to tolerate.)