For choosing the best Python testing framework, the below points should be taken into consideration:

If the quality and structure of the scripts, is fulfilling your purposes. The programming script should be easy to understand/maintain and free of defects.

The programming structure of Python plays an important role in choosing the testing framework which consists – Attributes, statements, functions, operators, modules and standard library files.

How easily you can generate tests and at what extent they can be reused?

The method adopted for test/test module execution (Module running techniques).